Clinical Testing

When purchasing new products, consumers search for ingredient listings, testing information and reassurances that products are effective. A Natural Difference not only has “safe for public use” approval on our entire product line, we also perform clinical trials. Our products are constantly checked for false claims and correct ingredient listings. Every new product is tested on humans for a period of six months to one year before it is added to our skin care line.


We are honored to join the ranks of other major United State skin care manufactures in exporting our product line to Europe and Australia. To receive “European Union” approval, a manufacturer must be reviewed and approved by two separate government laboratories in Germany. Both laboratories analyze and test submitted products and individual ingredients with two testing formats.

Injecting bacteria into formulations to determine shelf-life

Thorough microscopic examination of all ingredients to “Safe for Public Use” approval
A Natural Difference was so diligent to comply with all rulings, we have been approved to export internationally. Since our European Union approval, we have had tremendous export sales growth in Europe and Australia. We look forward to increased international distribution in other countries around the world.

Nobel Prize Winning Ingredients

“Telomeres and Epigrowth Factor, the perfect pair for cellular longevity.”


In 2009, winners Elizabeth H. Blackburn, Carol W. Greider, and Jack W. Szostak, discovered how chromosomes are protected by telomeres and the enzyme telomerase. Their discoveries had added a new dimension to our understanding of cells, shed light on disease mechanisms, and stimulated the development of potential new therapies .

EGF Epidermal Growth Factor

Rita Levi Montalcini and Stanley Cohen received the Noble Piece prize in 1986 for their discoveries of “growth factors.“ In their studies, epidermal growth factors, EGF, was shown to enhance the healing of wounds by stimulating growth of cells. EGF became the number one ingredient to be use after all peelings by an A Natural Difference Esthetician.